BcII RFLP in fucosidase pseudogene (FUCA1P)

NcoI RFLP in the pseudogene (CYP2D8P) of the human debrisoquine 4-hydroxylase locus.

Deletion of PTENP1 pseudogene in human melanoma

1. Poliseno, L., et al., Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Ernst, A., et al., De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Dikst...

Current Trends in Pseudogene Detection and Characterization

Pseudogenes are homologous relatives of known genes that have lost their ability to function as a transcriptional unit. Three classes of pseudogenes are known to exist: duplicated pseudogenes; processed or retrotransposed pseudogenes; and unitary or disabled pseudogenes. Since pseudogenes may display a number of the characteristics of functional genes, they pose a unique set of problems for ab ...

A pseudogene-signature in glioma predicts survival

Pseudogene was recognized as a potential tumor suppressor or oncogene in varies of diseases, however its roles in glioma have not been investigated. Our study was to identify the pseudogene-signature that predicted glioma survival. Using a pseudogene-mining approach, we performed pseudogene expression profiling in 183 glioma samples from the Chinese Glioma Genome Atlas (CGGA) and set it as the ...

Cloning of a kallikrein pseudogene.

OBJECTIVES Kallikreins are a group of serine proteases clustered together on a small region of chromosome 19q13.4. Recent reports suggest that kallikreins are differentially expressed in malignancy and have potential as cancer biomarkers. The human kallikrein gene locus has now been fully characterized and 15 functional kallikreins were identified. Although many kallikrein pseudogenes have alre...